Popular Conditions & Diets
Known by early Greek and Roman civilizations as the Nectar of the Gods, referred to in the Hittite code, found within ancient Babylonian and Sumerian cuneiforms, and Egyptian and Indian sacred scripts, honey has been written into history since, well, since history began to be written.
Each teaspoon of delicious golden honey contains the nectars of 5,000 summer flowers, personally collected one flower at a time by a devoted worker bee.
Though a painstakingly complex process, honey is essentially the storage format of bee food, meticulously tended to and preserved in the comb for hungrier winter months.
And store it does: honey never goes bad. If you found a jar of it deep in the catacombs of the Egyptian pyramids, you would be able to enjoy it as though it had been tapped from the hive yesterday.
Fructose, glucose, maltose, erlose, panose, and maltotriose …
On a microscopic level, honey is a sophisticated crystalline matrix of mono, di, and more complex oligosaccharides aka sugars! Some of these more elaborate sugar structures form perfect prebiotics. Prebiotics are essentially food for healthy bacteria in the gut.
Adding honey to probiotic foods like yogurt is a great way to create the perfect combination of probiotics and prebiotics.
But it’s not so much the microbes fed by honey that make it unique - it’s the microbes killed by honey!
Yes, honey is possibly the single most potent antibiotic food produced by nature, aside from garlic.
Honey antagonizes over 250 strains of bacteria that might threaten our health. Many of these bacteria, like deadly MRSA, have evolved beyond susceptibility to common antibiotics and thus have positioned natural honey for a renaissance of recognition in medical science.
Much of honey’s ability to inhibit or outright kill nasty bugs is thanks to its naturally high levels of hydrogen peroxide.
This natural disinfectant, made by some white blood cells, protects against intruders by inflicting them with oxidative stress.
The levels of hydrogen peroxide in honey seem to be perfectly balanced to support our defenses against bacteria without unleashing enough free radicals to harm our cells.
The water content in honey is very low.
Primarily composed of different sugars, the remaining balance is hygroscopic, meaning it draws moisture from its surroundings. Just as with salt, humanity’s first refrigerator, this sponge-like effect deprives opportunistic bacteria of the terrain they need to survive.
However, instead of drying out wounds, honey’s osmotic power summons surrounding lymphatic fluids to bring immune cells to the location.
The incoming water from plasma and lymph allows the honey to produce more hydrogen peroxide enzymatically.
This property has made honey of great topical use for cuts, bruises, abrasions, and other surface injuries, applications for which honey continues to be used in hospitals globally.
Manuka flowers only grow in New Zealand, and the honey bees make from their nectar fetches quite a sum: high-end Manuka honey can cost a hundred times the price of regular honey.
Peter Molan, a New Zealand professor, first discovered the fascinating antibacterial qualities of Manuka honey in the 1980s. It wasn’t until 2008 that methylglyoxal (MGO) was explicitly named- a highly active bactericidal honey component unrelated to hydrogen peroxide.
Antibiotic resistance is a genuine and growing concern. But, as far as we know, pathogens cannot develop any ability to withstand Manuka compounds.
Helicobacter pylori, the bacteria that causes stomach and small intestine ulcers, is powerfully inhibited by honey rich in MGO, as are many other strains of nasty bugs. It benefits bees too, by fighting off pathogens that threaten them, such as Nosema apis, a common single-celled parasite.
Manuka honey can also infiltrate biofilms, the sticky structures that multiple bacterial species use as a bunker to shield themselves from the immune system.
MGO appears to be primarily responsible for this remarkable ability.
Unique Manuka Factor (UMF) offers a lab-verifiable standard of antibacterial activity and sets authentic medicinal Manuka honey apart from disingenuous blends or knockoffs. Anything higher than UMF 10+ is considered a clinical grade, something to keep in mind if you decide to invest in this top-shelf honey.
Most bacteria flourish in slightly basic pH levels, but honey is about as acidic as grapefruit juice.
This quality alone wouldn’t achieve much, but honey’s low pH works in tandem with its hydrogen peroxide, natural osmosis effect, and other mixed phytochemicals to create a potent multifaceted antibiotic.
The bees collect phytonutrients, including phenols, terpenes, and organic acids, from flower nectar.
No honey has received more attention than the genuinely remarkable methylglyoxal found in authentic Manuka honey from New Zealand.
Honey is a complex and beautiful thing in its natural and unprocessed state.
But hydrogen peroxide, live yeasts, allergy-busting bee pollen, antioxidants, and enzymes like diastase, invertase, and glucose oxidase (the enzyme that creates hydrogen peroxide) are destroyed or deactivated by heat exceeding 37 degrees celsius. So look for raw, unpasteurized honey and avoid cooking it or overheating it.
A single ounce of delicious golden honey represents the combined efforts of no fewer than 1,000 different buzzing bees.
Honour their hard work with some of our favourite honey-featuring recipes.
al Somal, N., Coley, K. E., Molan, P. C., & Hancock, B. M. (1994). Susceptibility of Helicobacter pylori to the antibacterial activity of manuka honey. Journal of the Royal Society of Medicine, 87(1), 9–12. https://doi.org/10.1177/014107689408700106
Altman, N. (2010). The Honey Prescription: The amazing power of honey as medicine. Retrieved March 3, 2023, from https://www.amazon.com/Honey-Prescription-Amazing-Power-Medicine/dp/1594773467
Andualem B. (2013). Combined antibacterial activity of stingless bee (Apis mellipodae) honey and garlic (Allium sativum) extracts against standard and clinical pathogenic bacteria. Asian Pacific journal of tropical biomedicine, 3(9), 725–731. https://doi.org/10.1016/S2221-1691(13)60146-X
Banaeian-Borujeni, S., Mobini, G. R., Pourgheysari, B., & Validi, M. (2013). Comparison of the effect of honey and miconazole against Candida albicans in vitro. Advanced biomedical research, 2, 57. https://doi.org/10.4103/2277-9175.115800
Carter, D. A., Blair, S. E., Cokcetin, N. N., Bouzo, D., Brooks, P., Schothauer, R., & Harry, E. J. (2016). Therapeutic Manuka Honey: No Longer So Alternative. Frontiers in microbiology, 7, 569. https://doi.org/10.3389/fmicb.2016.00569
Carvalho, C. M., Meirinho, S., Estevinho, M. L. F., & Choupina, A. (n.d.). Yeast species associated with honey: Different identification methods. Retrieved March 3, 2023, from https://www.researchgate.net/publication/288352904_Yeast_species_ associated_with_honey_different_identification_methods
Deng, J., Liu, R., Lu, Q., Hao, P., Xu, A., Zhang, J., & Tan, J. (2018). Biochemical properties, antibacterial and cellular antioxidant activities of buckwheat honey in comparison to manuka honey. Food chemistry, 252, 243–249. https://doi.org/10.1016/j.foodchem.2018.01.115
Dezmirean, G. I., Mărghitaş, L. A., Bobiş, O., Dezmirean, D. S., Bonta, V., & Erler, S. (2012). Botanical origin causes changes in nutritional profile and antioxidant activity of fermented products obtained from Honey. Journal of Agricultural and Food Chemistry, 60(32), 8028–8035. https://doi.org/10.1021/jf3022282
Geiling, N. (2013, August 22). The Science Behind Honey's Eternal Shelf Life. Smithsonian Magazine. Retrieved March 3, 2023, from https://www.smithsonianmag.com/science-nature/the-science-behind-honeys-eternal-shelf-life-1218690/?no-ist
Glucina, L. (2022, January 11). Fermented Garlic Honey. Ascension Kitchen. Retrieved March 3, 2023, from https://ascensionkitchen.com/fermented-garlic-honey/
Ilse Knatz Ortabasi. (2010, June 17). Honey Bees - Natural history 1. YouTube. Retrieved March 3, 2023, from https://www.youtube.com/watch?v=x7cX2cjFunw
Ilse Knatz Ortabasi. (2010, June 17). Honey Bees - Natural history 2. YouTube. Retrieved March 3, 2023, from https://www.youtube.com/watch?v=VsCmSWoF8PY
Insider Business. (2019, May 25). Why mānuka honey is so expensive | so expensive. YouTube. Retrieved March 3, 2023, from https://www.youtube.com/watch?v=j6bGZXk6F2E
Irish, J., Carter, D. A., Shokohi, T., & Blair, S. E. (2006). Honey has an antifungal effect agains candida species. Medical Mycology, 44(3), 289–291. https://doi.org/10.1080/13693780500417037
Johnston, M., McBride, M., Dahiya, D., Owusu-Apenten, R., & Nigam, P. S. (2018). Antibacterial activity of Manuka honey and its components: An overview. AIMS microbiology, 4(4), 655–664. https://doi.org/10.3934/microbiol.2018.4.655
Kilty, S. J., Duval, M., Chan, F. T., Ferris, W., & Slinger, R. (2011). Methylglyoxal: (active agent of manuka honey) in vitro activity against bacterial biofilms. International forum of allergy & rhinology, 1(5), 348–350. https://doi.org/10.1002/alr.20073
Lane, J., Calonne, J., Slattery, H., & Hickey, R. M. (2019). Oligosaccharides isolated from MGO™ manuka honey inhibit the adhesion of pseudomonas aeruginosa, escherichia coli O157:H7 and Staphylococcus aureus to human HT-29 cells. Foods, 8(10), 446. https://doi.org/10.3390/foods8100446
Lu, J., Turnbull, L., Burke, C. M., Liu, M., Carter, D. A., Schlothauer, R. C., Whitchurch, C. B., & Harry, E. J. (2014). Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities. PeerJ, 2, e326. https://doi.org/10.7717/peerj.326
MacPherson, R. (2022, October 7). Why you should add oligosaccharides to your diet. Verywell Fit. Retrieved March 3, 2023, from https://www.verywellfit.com/oligosaccharides-and-prebiotics-health-benefits-2242223
Mohan, A., Quek, S.-Y., Gutierrez-Maddox, N., Gao, Y., & Shu, Q. (2017). Effect of honey in improving the gut microbial balance. Food Quality and Safety, 1(2), 107–115. https://doi.org/10.1093/fqsafe/fyx015
Moussa, A., Noureddine, D., Saad, A., Abdelmelek, M., & Abdelkader, B. (2012). Antifungal activity of four honeys of different types from Algeria against pathogenic yeast: Candida albicans and Rhodotorula sp. Asian Pacific journal of tropical biomedicine, 2(7), 554–557. https://doi.org/10.1016/S2221-1691(12)60096-3
Nep Tech. (2018, December 12). How honey bees pass through life and death. YouTube. Retrieved March 3, 2023, from https://www.youtube.com/watch?v=TSS1wyZBTi0
Osato, M. S., Reddy, S. G., & Graham, D. Y. (1999). Osmotic effect of honey on growth and viability of Helicobacter pylori. Digestive diseases and sciences, 44(3), 462–464. https://doi.org/10.1023/a:1026676517213
Shahzad, A., & Cohrs, R. J. (2012). In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles. Translational biomedicine, 3(2), 2. https://doi.org/10.3823/434
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